Cucurbit[8]uril templated supramolecular ring structure formation and protein assembly modulation.

نویسندگان

  • Mellany Ramaekers
  • Sjors P W Wijnands
  • Joost L J van Dongen
  • Luc Brunsveld
  • Patricia Y W Dankers
چکیده

The interplay of Phe-Gly-Gly (FGG)-tagged proteins and bivalent FGG-tagged penta(ethylene glycol) as guest molecules with cucurbit[8]uril (Q8) hosts is studied to modulate the supramolecular assembly process. Ring structure formation of the bivalent guest molecule with Q8 leads to enhanced binding properties and efficient inhibition of protein assemblies.

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عنوان ژورنال:
  • Chemical communications

دوره 51 15  شماره 

صفحات  -

تاریخ انتشار 2015